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Medical Imaging

Videomicroscopic Semi-Shadow Visualization of LoC-Si (Lab-on-a-Chip_[based_on]_Silicone) test structures from Institute of Molecular Electronics (D. Shevchenko; founder of Scientific and Production Association "Microbiotechniques" Ltd.) and Russian Academy of Sciences (INEPCP RAS; ICP RAS)

 

Vis. Tech.: MBS-10 Binocular Stereoscopic Microscope; Indirect Angular Illumination.

 

Found.: Initiative project (D. Shevchenko, O. Gradov; 2015-2016)

 

Fab.: JSC “Voskhod” KRLZ*

 

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Modified characteriograph-assisted testings of spectrozonal analog lab-on-a-chip under laser beams

 

Acknowledgements:

  • “Development of the novel physical methods for complex biomedical diagnostics based on position-sensitive mapping with the angular resolution at the tissue and cellular levels using analytical labs-on-a-chip” (RFBR grant # 16-32-00914) [6 838,27 $ per year; 2016-2017];
  • “Lab-on-a-chip development for personalized diagnostics” (FASIE grant 0019125) [3 039,00 $ per year; 2016-2017].
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Testings of spectrozonal analog lab-on-a-chip with angle-sensitive pixels (ASP) using diode laser sources in combined nanosecond reflectometric and stroboscopic oscilloscopic measurements.

 

FILE 1: Combined nanosecond reflectometric and stroboscopic oscilloscopic analysis for RF lab-on-a-chip.mp4

00:15 - Wavelength: 405 nm (DPSS);

00:57 - Wavelength: 650 nm (laser diode source);

 

FILE 2: Analog angle-sensitive pixel lab-on-a-chip testing using nanosecond stroboscopic oscilloscope.mp4

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In this study, adaptive hybrid (AH) scheme is proposed to enhance the measurement accuracy of conventional CD method to acquire the 2-dimensional velocity field of blood flows. It can offer the assistance of the velocity field information measured preliminarily using ultrasound speckle image velocimetry (SIV) technique. Consequently, erroneous vectors in the CD results were replaced with the SIV results. The performance of the proposed AH method was validated by varying flow rate and insonation angle. We compared the AH method with the CD and SIV methods in an agarose vessel model.

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Background: Retinopathy of prematurity (ROP) is one of the main causes of childhood blindness. However, insufficient ophthalmologists are qualified for ROP screening. Objective: To evaluate the performance of a deep neural network (DNN) for automated screening of ROP. Methods: The training and test sets came from 420,365 wide-angle retina images from ROP screening. A transfer learning scheme was designed to train the DNN classifier. First, a pre-processing classifier separated unqualified images. Then, pediatric ophthalmologists labeled each image as either ROP or negative.
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This dataset is for the paper titled: Segmentation of Cervical Cell Images based on Generative Adversarial Networks. The dataset is used to train and test the Cell-GAN, a generative adversarial network. After training, the Cell-GAN is able to generate a complete single-cell image which has the similar contour to the cell to be segmented.

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