Biomedical and Health Sciences

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, 490 ductal (IDC), and 88 mixed IDC/ILC. Besides E-cadherin loss, the best known ILC genetic hallmark, we identified mutations targeting PTEN, TBX3 and FOXA1 as ILC enriched features. PTEN loss associated with increased AKT phosphorylation, which was highest in ILC among all breast cancer subtypes. Spatially clustered FOXA1 mutations correlated with increased FOXA1 expression and activity.

The accurate prediction of new interactions between drugs is important for avoiding unknown (mild or severe) adverse reactions to drug combinations. The development of effective in silico methods for evaluating drug interactions based on gene expression data requires an understanding of how various drugs alter gene expression. Current computational methods for the prediction of drug-drug interactions (DDIs) utilize data for known DDIs to predict unknown interactions. However, these methods are limited in the absence of known predictive DDIs.

EEG signals of various subjects in text files are uploaded. It can be useful for various EEG signal processing algorithms- filtering, linear prediction, abnormality detection, PCA, ICA etc.

This dataset is very vast and contains Bengali tweets related to COVID-19. There are 36117 unique tweet-ids in the whole dataset that ranges from December 2019 till May 2020 . The keywords that have been used to crawl the tweets are 'corona',  ,  'covid ' , 'sarscov2 ',  'covid19', 'coronavirus '.  For getting the other 33 fields of data drop a mail at "avishekgarain@gmail.com". Code snippet is given in Documentation file. Sharing Twitter data other than Tweet ids publicly violates Twitter regulation policies.