Machine Learning

We develop a general group-based continuous-time Markov epidemic model (GgroupEM) framework for any compartmental epidemic model (e.g., susceptible-infected-susceptible, susceptible-infected-recovered, susceptible-exposed-infected-recovered). Here, a group consists of a collection of individual nodes of a network. This model can be used to understand the critical dynamic characteristics of a stochastic epidemic spreading over large complex networks while being informative about the state of groups.

Machine learning offers a wide range of techniques to predict medicine expenditures using historical expenditures data as well as other healthcare variables. For example, researchers have developed multi-layer perceptron (MLP), long-short term memory (LSTM), and convolutional neural networks (CNN) for predicting healthcare outcomes. However, recently proposed generative approaches (e.g., generative adversarial networks; GANs) are yet to be explored for time-series prediction of medicine-related expenditures.

Evidence-Based Medicine (EBM) aims to apply the best available evidence gained from scientific methods to clinical decision making. A generally accepted criterion to formulate evidence is to use the PICO framework, where PICO stands for Problem/Population, Intervention, Comparison, and Outcome. Automatic extraction of PICO-related sentences from medical literature is crucial to the success of many EBM applications. In this work, we present our Aceso system, which automatically generates PICO-based evidence summaries from medical literature.

The dataset consists of two populations of fetuses: 160 healthy and 102 Late Intra Uterine Growth Restricted (IUGR). Late IUGR is an adverse pathological condition encompassing chronic hypoxia as a consequence of placental insufficiency, resulting in an abnormal rate of fetal growth. In standard clinical practice, Late IUGR diagnosis can only be suspected in the third trimester and ultimately confirmed at birth. This data collection comprises of a set of 31 Fetal Heart Rate (FHR) indices computed at different time scales and domains accompanied by the clinical diagnosis.