lab-on-chip
This video demonstrates the real-time data acquisition and noise reduction capabilities of a CMOS capacitive sensor array (CSA) implemented on an FPGA. The system captures the evaporation process of a deionized water droplet placed on the sensor array, using multiple sampling (MS) and pixel-wise accumulation (PWA) techniques to enhance signal quality and reduce random noise. The system efficiently processes and transmits the data, showcasing the gradual reduction in the droplet's size as it evaporates.
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Monitoring cell viability and proliferation in real-time provides a more comprehensive picture of the changes cells undergo during their lifecycle than can be achieved using traditional end-point assays. Our lab has developed a CMOS biosensor that monitors cell viability through high-resolution capacitance measurements of cell adhesion quality. The system consists of a 3 × 3 mm2 chip with an array of 16 sensors, on-chip digitization, and serial data output that can be interfaced with inexpensive off-the-shelf components.
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