Epilepsy
Transfer RNAs (tRNAs) are a family of non-coding ribonucleic acids (RNAs) that are involved in protein translation. Cleavage of tRNA through stress-induced ribonucleases results in the production of short tRNA-derived small RNAs (tsRNAs), such as tRNA-derived fragments (tRFs). Recent studies have identified three tRFs - 5'AlaTGC, 5'GluCTC, and 5'GlyGCC - to be released from neurons and significantly elevated in epilepsy patients. Extracellular 5'tRFs are taken up by neurons and act in paracrine to inhibit protein translation.
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Synthetic Epileptic Spike EEG Database (SESED-WUT)
The database contains EEG, EMG, and EOG signals with artificially generated epileptic spikes. The recordings were performed using the g.USBamp 2.0 amplifier. Data were collected from 5 EEG channels (C3, Cz, C4, Fz, Fp1), 1 EOG channel (VEOG), and 3 EMG channels (Nape, Cheek, Jaw). The signals were sampled at 256 Hz and processed with a bandpass filter (0.1–100 Hz) and a notch filter (48–52 Hz).
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The study included 50 epilepsy patients undergoing long-term video-EEG monitoring at the Epilepsy Center of Guangdong 999 Brain Hospital. The inclusion criteria for patients were as follows: (1) VEEG reports confirming definite epileptic seizures, (2) complete video data containing both seizure and non-seizure periods, (3) no intentional interference during patient seizures, and no occlusion of the patient, such as patients were covered by quilts.
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The following keywords are used to create this database-
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