PVA Hydrogel Lens Characterization

Citation Author(s):
Mayank
Goswami
IIT Roorkee
Submitted by:
mayank goswami
Last updated:
Tue, 07/16/2024 - 02:54
DOI:
10.21227/knnq-d844
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Abstract 

The ocular diseases rising from vascular endothelial growth factors (VEGF) is rising on an alarming rate. Mostly the complex retinal disorders are resulted from overexpression of VEGF. Common ocular complications such as age related macular edema (AMD) (over 196 million), diabetic retinopathy (DR) (over 103.12 million) and retinal vein occlusion can result to permanent vision loss if not treated early. Early treatment of such complications is inhibiting the VEGF signaling cascade via anti-VEGF therapy. Common drug administration involves topical eye drop which limits the percentage of bioavailability. Similarly, panretinal photocoagulation or intra/intervitreal administration through injections can lead to retinal scars/injury. PVA-based Hydrogel Ocular Lens characterization data is appended here. This can also be used as a Platform to construct Smart Lens. The Data contains Transmittance, Drug Delivery, biotoxicity, SEM, Swelling, Surface Roughness, and encapsulation, time relevance for the Lens. 

Instructions: 

figure wise data set is given.