Diffusion and Displacement Encoded MRI Dataset to Estimate In Vivo Cardiomyocyte Strain

Changes in left ventricular (LV) aggregate cardiomyocyte  orientation and deformation underlie cardiac function and dysfunction. As such, in vivo aggregate cardiomyocyte "myofiber" strain has mechanistic significance, but currently there exists no established technique to measure in vivo cardiomyocyte strain.

The following dataset contains Dispalcement Encoding with Stimulated Echoes (DENSE) MRI and cardiac Diffusion Tensor Imaging (cDTI) data. The functional data from DENSE MRI along with the microstructural data reconstructed from cDTI can be used to compute strain along the cardiomyocyte axis.