This repository introduces a novel dataset for the classification of Chronic Obstructive Pulmonary Disease (COPD) patients and Healthy Controls. The Exasens dataset includes demographic information on 4 groups of saliva samples (COPD-HC-Asthma-Infected) collected in the frame of a joint research project, Exasens (https://www.leibniz-healthtech.de/en/research/projects/bmbf-project-exasens/), at the Research Center Borstel, BioMaterialBank Nord (Borstel, Germany).