Serious games (SGs) are innovative technological solutions to support children and adults with Autism Spectrum Disorder (ASD). We designed and developed a 3D personalized SG aimed to support children and teens with ASD in practicing a specific daily living activity: shopping in a supermarket. In our experiment, ten participants with ASD (8 males/2 females; age range 8-16 years) played ten game sessions, one per week, for no more than 30 minutes.