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SYNTHETIC ELECTRORETINOGRAM SIGNALS FOR ENHANCING CLASSIFICATION OF AUTISM SPECTRUM DISORDER

Citation Author(s):
Mikhail Kulyabin (Pattern Recognition Lab, University of Erlangen-Nuremberg, Germany)
Paul A. Constable (College of Nursing and Health Sciences, Caring Futures Institute, Flinders University, Australia)
Aleksei Zhdanov (Siemens Healthineers, Erlangen, Germany)
Irene O. Lee (Behavioural and Brain Sciences Unit, Population Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK)
David H. Skuse (Behavioural and Brain Sciences Unit, Population Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK)
Dorothy A. Thompson (The Tony Kriss Visual Electrophysiology Unit, Clinical and Academic Department of Ophthalmology, Great Ormond Street Hospital for Children NHS Trust, London, UK)
Andreas Maier (Pattern Recognition Lab, University of Erlangen-Nuremberg, Germany)
Submitted by:
Mikhail Kulyabin
Last updated:
DOI:
10.21227/npv7-8063
Data Format:
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Abstract

The electroretinogram (ERG) is a clinical test that records the retina's electrical response to light. The ERG is a promising way to study different neurodevelopmental and neurodegenerative disorders, including Autism Spectrum Disorder (ASD) - a neurodevelopmental condition that impacts language, communication, and social interactions. However, privacy issues and a lack of data complicate Artificial Intelligence applications in this domain. Synthetic ERG signals generated from real ERG recordings should carry similar information and could be used as an extension for natural data. The synthetic dataset consists of ASD and Control with flash strengths of 1.204, 1.114, 0.949, and 0.799 (log cd.s.m^−2). Synthetic reference signals can enhance medical operational efficiency by offering a feasible alternative to natural ones. Synthesizing facilitates dataset expansion within specialized domains, enabling training resource-intensive networks such as transformers.

Instructions:

Dataset consists of 8 CSV files of ASD and Control synthetic ERG signals of 4 flash strength.