The 3DLSC-COVID datset includes a total of 1,805 3D chest CT scans with more than 570,000 CT slices were collected from 2 standard CT scanners of Liyuan Hospital, i.e., UIH uCT 510 and GE Optima CT600. Among all CT scans, there were 794 positive cases of COVID-19, which were further confirmed by clinical symptoms and RT-PCR from January 16 to April 16, 2020.