Protein-Protein Negative Interaction; Protein-Protein Interaction; Protein-Protein Interaction Prediction; Protein Negative Sampling; Machine Learning

This is a protein negative interaction dataset, generated by our proposed method the “Features Dissimilarity-based Negative Generation” approach to generate protein negative sampling based on sequence data. It measures similarity of sequence characteristics without alignment based on Protein similarity. It achieved results of 97% compared to randomly generated negative dataset.