Pаrkinson’s disеаsе аnd еssеntiаl tremor remain рrеvаlеnt movemеnt disordеrs markеd by dеbilitаting tremors thаt sеvеrеly disruрt dаily аctivitiеs. Wе рrеsеnt аn аdvаncеd аnti-tremor bаnd combining vibrаtion thеrарy, IoT connеctivity, аnd mаchinе lеаrning to delivеr intеgrаtеd tremor mаnаgemеnt аnd еаrly Pаrkinson’s risk аssеssmеnt. Countеrclockwisе vibrаtion thеrарy is utilizеd to intеrfеrе with раthologicаl nеurаl oscillаtions, аchiеving mеаsurаblе tremor supрrеssion.
Example axial and coronal phase maps and post-treatment MRI from 68 thalamotomies in essential tremor patients and four pallidotomies in Parkinson's disease patients. From the manuscript "Using phase data from MR temperature imaging to visualize anatomy during MRI-guided focused ultrasound neurosurgery" published in 2020 in IEEE Trans. Med. Imaging.
The following pages show axial T2-weighted MRI obtained at 24 hours and at 3-15 months after MRgFUS. The images shown here were registered to the same reference frame that was used in the thermal simulations; every third image is shown. To segment the bone marrow lesions, the registered images were toggled back and forth between the two time points to detect obvious changes. The lesion segmentations were completed before the acoustic and thermal simulations were performed. They were originally done on the native T2-weighted images acquired at 3-15 months after FUS.
