cellular biophysics

Co-cultures are a traditional method for studying the cellular properties of cell to cell interactions among different cell types. How network properties in these multicellular synthetic systems vary from monocultures are of particular interest. Understanding the changes in the functional output of these in vitro spiking neural networks can provide new insights into in vivo systems and how to develop biological system models that better reflect physiological conditions - something of paramount importance to the progress of synthetic biology.