Dataset for Advanced Plaque Modeling for Atherosclerosis Detection using Molecular Communication

Citation Author(s):
Pit
Hofmann
Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, Dresden, Germany
Alexander
Wietfeld
Chair of Communication Networks, Technical University of Munich, Munich, Germany
Jonas
Fuchtmann
MITI, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
Pengjie
Zhou
Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, Dresden, Germany
Ruifeng
Zheng
Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, Dresden, Germany
Juan
Cabrera
Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, Dresden, Germany
Frank H.P.
Fitzek
Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, Dresden, Germany; Centre for Tactile Internet with Human-in-the-Loop (CeTI), Dresden, Germany
Wolfgang
Kellerer
Chair of Communication Networks, Technical University of Munich, Munich, Germany
Submitted by:
Pit Hofmann
Last updated:
Mon, 11/11/2024 - 19:48
DOI:
10.21227/mn8d-0h55
License:
Creative Commons Attribution
58 Views
Categories:
Communications
Keywords:
Internet of Bio-Nano Things, Microfluidic Molecular Communication, OpenFOAM, Plaque Formations, Simulation
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Abstract 

This dataset contains the simulation results for the microfluidic molecular simulation for advanced plaque modeling using the OpenFOAM MPPIC solver. In addition to the simulation results, first simulation results for fluid-solid interaction are uploaded using the solids4foam toolbox.

Publication:

Alexander Wietfeld, Pit Hofmann, Jonas Fuchtmann, Pengjie Zhou, Ruifeng Zheng, Juan A. Cabrera, Frank H.P. Fitzek, and Wolfgang Kellerer, “Advanced Plaque Modeling for Atherosclerosis Detection Using Molecular Communication,” submitted to International Communications Conference 2025, SAC — Molecular, Biological, and Multi-Scale Communications, June 2025.

Brief Explanation of the OpenFOAM Structure:

  • File for visualization and post-processing of simulation results in, e.g., Paraview: foam.foam
  • Mesh created with, e.g., Salome: 4.unv (For a description of the numbering, please see below.)
  • A system directory is designated for configuring the parameters related to the solution procedure. This directory includes at least three essential files:

                    - controlDict: This file is responsible for establishing run control parameters, encompassing aspects such as the start and end time, time step settings, and parameters for data output.
                    - fvSchemes: Within this file, users can dynamically select discretization schemes employed during the solution process.
                    - fvSolution: In this file, users can define equation solvers, tolerance levels, and various algorithm controls required for the current run.

  • Within the constant directory, comprehensive information about the case mesh is stored. This directory also hosts subdirectories like polyMesh, which house detailed descriptions of the mesh, along with files that define the physical properties relevant to the specific application. An example of such a file is transportProperties.
  • The time directories house individual data files pertaining to specific fields. This data can encompass two distinct types: either the initial values and boundary conditions, which necessitate user specification to define the problem, or results generated by OpenFOAM and saved to files. The initial conditions are typically stored in a directory named "0".

 

Instructions: 

Package:

* Naming of the various simulation scenarios: Given the example "Plaque_laminar_1_varying_016", "Plaque" denotes the existing plaque in the model, "laminar" assumes laminar flow, "1" denotes the plaque size (1 -> no plaque, 4 -> r_p = 0.25 x r_c, 7 -> r_p = 0.5 x r_c, 10 -> r_p = 0.75 x r_c), "varying" denotes the given pulsatile inlet velocity boundary condition, and "016" the release time of the particles (016 -> t_release = 0.16 s, 04 -> t_release = 0.4 s, 09 -> t_release = 0.9 s).

For further instructions, please refer to the publication.

 

Funding Agency: 
German Federal Ministry of Education and Research (BMBF) & German Research Foundation (DFG)
Grant Number: 
16KISK001K, 16KISK002 and 16KIS1994 (BMBF) & EXC 2050/1 – Project ID 390696704 – Cluster of Excellence “Centre for Tactile Internet with Human-in-the-Loop” (CeTI)

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