The datset inculed the BrainWeb data which consists of T1-weighted (T1w), T2-weighted (T2w), and proton density-weighted (PDw) normal brain noise-free MR images (the size is with resolution), two real T1w MR brain datasets (OAS30040 and OAS30072) from the Open Access Series of imaging Studies (OASIS) database,and the synthetic DW-MRI dataset