The following pages show axial T2-weighted MRI obtained at 24 hours and at 3-15 months after MRgFUS. The images shown here were registered to the same reference frame that was used in the thermal simulations; every third image is shown. To segment the bone marrow lesions, the registered images were toggled back and forth between the two time points to detect obvious changes. The lesion segmentations were completed before the acoustic and thermal simulations were performed. They were originally done on the native T2-weighted images acquired at 3-15 months after FUS.