70 images with a total of more than 2 GB of data have been employed for the experimental evaluation. All images are acquired at 24 bpp with 8 bits per pixel per component (bpppc). They depict various tissues of different sizes and stained with Hematoxylin and Eosin (H\&E) stain. The tissues employed in the experiments are skin fibroblast (SKNF), endometrial (END), lung (LNGF), embryonic stem cells (ES), kidney clear cell carcinoma (KIRC), pancreas (PANC), brain glioblastoma multiforme (GBM), colon adenocarcinoma (COAD), and lymphatic (LYMP).