The dataset contains 208 patient scans that spread over three parts of anatomy(head, neck, and pelvis). The dataset aims to establish accurate anatomical correspondences between MegaVoltage Planar Digital Radio-graphs (MV-DRs) andKiloVoltage Digital Reconstructed Radiographs (KV-DRRs), which are widely used in Image-Guided Radiation Therapy (IGRT) to verify patients’ positions for accurate radiotherapy delivery.