Monitoring cell viability and proliferation in real-time provides a more comprehensive picture of the changes cells undergo during their lifecycle than can be achieved using traditional end-point assays. Our lab has developed a CMOS biosensor that monitors cell viability through high-resolution capacitance measurements of cell adhesion quality. The system consists of a 3 × 3 mm2 chip with an array of 16 sensors, on-chip digitization, and serial data output that can be interfaced with inexpensive off-the-shelf components.

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Documentation: 
[1] Bathiya Senevirathna, Sheung Lu, Marc Dandin, John Basile, Elisabeth Smela, Pamela Abshire, "Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging", IEEE Dataport, 2019. [Online]. Available: http://dx.doi.org/10.21227/9zzd-w936. Accessed: Apr. 15, 2024.
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doi = {10.21227/9zzd-w936},
url = {http://dx.doi.org/10.21227/9zzd-w936},
author = {Bathiya Senevirathna; Sheung Lu; Marc Dandin; John Basile; Elisabeth Smela; Pamela Abshire },
publisher = {IEEE Dataport},
title = {Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging},
year = {2019} }
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T1 - Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging
AU - Bathiya Senevirathna; Sheung Lu; Marc Dandin; John Basile; Elisabeth Smela; Pamela Abshire
PY - 2019
PB - IEEE Dataport
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Bathiya Senevirathna, Sheung Lu, Marc Dandin, John Basile, Elisabeth Smela, Pamela Abshire. (2019). Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging. IEEE Dataport. http://dx.doi.org/10.21227/9zzd-w936
Bathiya Senevirathna, Sheung Lu, Marc Dandin, John Basile, Elisabeth Smela, Pamela Abshire, 2019. Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging. Available at: http://dx.doi.org/10.21227/9zzd-w936.
Bathiya Senevirathna, Sheung Lu, Marc Dandin, John Basile, Elisabeth Smela, Pamela Abshire. (2019). "Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging." Web.
1. Bathiya Senevirathna, Sheung Lu, Marc Dandin, John Basile, Elisabeth Smela, Pamela Abshire. Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging [Internet]. IEEE Dataport; 2019. Available from : http://dx.doi.org/10.21227/9zzd-w936
Bathiya Senevirathna, Sheung Lu, Marc Dandin, John Basile, Elisabeth Smela, Pamela Abshire. "Measurements of cancer cell proliferation using a Lab-on-CMOS capacitance sensor with time-lapse imaging." doi: 10.21227/9zzd-w936