Machine learning offers a wide range of techniques to predict medicine expenditures using historical expenditures data as well as other healthcare variables. For example, researchers have developed multi-layer perceptron (MLP), long-short term memory (LSTM), and convolutional neural networks (CNN) for predicting healthcare outcomes. However, recently proposed generative approaches (e.g., generative adversarial networks; GANs) are yet to be explored for time-series prediction of medicine-related expenditures.