<p>This dataset contains simulation results generated in OptiSystem for an 18‐tupling optical communication system. The parameters include optical source settings, modulator configurations, and a range of power and signal quality metrics. Key performance indicators—such as total power penalty (TPP), signal power penalty (SPP), and RMS jitter—are provided for each set of simulation inputs. The data are intended to facilitate reproducible research and to enable further analysis of high‐order frequency multiplication in optical networks.